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The F-Stuff

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The F Stuff ... and some basic genetic inheritance ... explained
To see how Poodle Specific or Labrador Specific disease causing genes can pass down the generations, meet up and wreak havoc in Labradoodles, hold your mouse over the picture below.
As you can see, if the gene is breed specific, like SA in the Poodle or prcd-PRA in the Labrador, it cannot produce affected individuals in the F1 generation, it can however, produce "carriers" of the disease.
Two F1's who are carriers for the gene can produce F2 puppies that are affected by the disease. The illustration below shows how an F3 puppy was "affected", because both of his parents were carriers and he inherited one dodgy gene from each parent.

The Founder Breeds are Labradors and Poodles

Both of these breeds have inherited genetic problems of the hips, eyes and elbows

F1's
are a result of crossing a Labrador and a Poodle (it doesn't matter which way round)

F1's
Because some genes are Lab or Poodle specific, they cannot meet in this 1st cross.

F2's
are the result of two F1's mating. If you mate an F1 back to a Lab or a Poodle their pups would be F1b's

F2's
But the problems can resurface here at the F2 level, where these genes can meet up again. Hence the absolute necessity for Health Testing.

F3's
are the result of two F2's mating. Two F3's will make an F4, etc.
An F1 mated to a F5 will still only produce F2's.

F3's
Don't believe the Hype! Contrary to popular belief, F3's can still shed and if bred from untested stock they may also have hip or eye problems...

Before someone jumps down my throat (and they probably will) can I state the obvious here ... these dogs are just illustrations. This diagram does not in any way imply that any of these dogs were ever bred to produce Labradoodles. No offence is intended or implied.

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